How miR-31-5p and miR-33a-5p Regulates SP1/CX43 Expression in Osteoarthritis Disease: Preliminary Insights
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چکیده
منابع مشابه
Differential expression of miR-1297, miR-3191-5p, miR-4435, and miR-4465 in malignant and benign breast tumors
Objective(s): MicroRNAs (miRs) are a class of small non-coding RNAs which are associated with tumor growth and progression. In the present study, we assessed the expression of selected miRs in malignant, benign, and adjacent normal breast tissues. Materials and Methods: The expression of miR-1297, miR-3191-5P, miR-4435, and miR-4465 were...
متن کاملDisease specific signature of circulating miR-150-5p and miR-21-5p in myasthenia gravis patients
PURPOSE Reliable biological markers for patients with the autoimmune neuromuscular disorder myasthenia gravis (MG) are lacking. We determined whether levels of the circulating immuno-microRNAs miR-150-5p and miR-21-5p were elevated in sera from clinically heterogeneous MG patients, with and without immunosuppression, as compared to healthy controls and patients with other autoimmune disorders. ...
متن کاملmiR-199a-5p regulates HIF-1α
Soft tissue sarcomas are a heterogeneous group of malignant neoplasms of mesenchymal origin. Partly due to hypoxia, an aggressive and radioresistant phenotype frequently develops, resulting in poorer patient outcome. microRNAs (miRNAs) are tiny, non-coding regulators of gene expression and in situations of cellular stress situations may predict clinical progression and patient outcome. In the p...
متن کاملPlasma miR-15b-5p, miR-338-5p, and miR-764 as Biomarkers for Hepatocellular Carcinoma
BACKGROUND Recently, increasing research evidence indicates that miRNA plays important roles in oncogenesis of hepatocellular carcinoma (HCC). The objective of this study was to investigate the potential of plasma miRNAs as biomarkers for HCC determination. MATERIAL AND METHODS This trial included 4 phases: (i) miRNAs in tumor tissues were screened with a miRNA array for determining candidate...
متن کاملمطالعه تغییرات بیان mir-411-5p و mir-299-5p در آدنوکارسینومای معده
چکیده: سرطان معده یکی از علل مرگ ومیر در جهان و به خصوص در کشورهای آسیایی می باشد. میکرو rna ها،rna های کوچک غیر کد کننده به طول 20-24 نوکلئوتید هستند که در تنظیم بیان ژن بعد از رونویسی نقش دارند. میکرو rna ها قادر به اتصال به ناحیه ترجمه نشدنی 3 ژن هدف هستند. این اتصال سبب تخریب mrna یا مهار ترجمه می شود. میکرو rna های بسیاری تاکنون در سلول های انسانی شناسایی شده است که در مراحل مختلف رشد و نم...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: 1422-0067
DOI: 10.3390/ijms22052471